Best NFL DFS Stacks Week 6: Lineup picks for DraftKings, FanDuel tournaments, daily fantasy football cash games


Bye weeks are starting in Week 6, and that means that NFL DFS slates will be a bit thinner than usual. There are four teams off in Week 6 and when you factor in the eight teams playing in stand-alone games, there are just 10 games and 20 teams from which to choose players on the DraftKings and FanDuel main slates. The condensed player pool will make stacking an even better strategy to use in daily fantasy football tournaments and cash games, as it can raise the ceiling of your lineups.

You usually want to look to pair a quarterback with a receiver or tight end when stacking. Those have the highest ceiling, but running back/defense stacks can have high floors. This week, those high-floor opportunities could prove important, as there aren’t a lot of great defensive matchups on the board. So, targeting positive defensive game scripts may be the way to go.

DraftKings continues to provide more variable pricing than FanDuel. That can be very useful in weeks like this with fewer options, but savvy daily fantasy players should check the prices on both sites. That can help shape lineup strategy and identify the undervalued players and sleepers that folks should be targeting this week.

Below are some of our favorite sets of teammates for DraftKings and FanDuel lineups this week. Be sure to follow our Twitter account @SN_Fantasy to see all of our DFS content heading into kickoff every week.

Week 6 NFL DFS Picks: Top cash game stacks for DraftKings, FanDuel

QB Patrick Mahomes, WR Tyreek Hill, & WR Mecole Hardman, Chiefs at Washington (DK/FD stack)

This feels like a nice bounce-back spot for the Chiefs. They were just humiliated by the Bills on Sunday Night Football, but now, they get a chance to take on the Washington Football Team.

Washington’s defense is giving up the sixth-most yards per game (407.8) and the second-most points per game (31) on the season. The Chiefs should be able to take advantage of this, and Mahomes will want to get in a rhythm early and try to make a statement that the Chief, despite being 2-3, are not done just yet.

Washington’s defense is particularly bad against receivers. They have given up the second-most receptions to WRs this year (79) and are one of four teams to allow at least 1,000 receiving yards and seven TDs to receivers this season. That should bode well for Hill, but it could also make Hardman, who is coming off a career-high nine catches against the Bills, a nice sleeper option.

You could justify trusting Travis Kelce instead of Hardman if you want to spend way up. You could also consider rolling with the inefficiently priced Darrel Williams, who will likely start in place of the injured Clyde Edwards-Helaire (knee) at running back. Either way, you can trust Mahomes and Hill together in some sort of stack, and given Washington’s poor performance against receivers, Hardman seems like the best play to earn a stack with lineup differentiation.

Quarterback | Running back | Wide receiver | Tight end | D/ST | Kicker

RB Darrell Henderson & Rams D/ST, Rams at Giants (DK/FD stack)

What do we know about the Giants’ offense right now? Well, in Week 5, Daniel Jones suffered a concussion, Saquon Barkley sprained his ankle, and Kenny Golladay suffered a hyperextended knee.

Will any of them play against the Rams? Barkley is out for sure, and the other two may have to miss time, as well. If they do, the Giants will be significantly shorthanded on offense, as Darius Slayton and Sterling Shepard are both dealing with hamstring injuries and Mike Glennon is the Giants’ backup quarterback.

The Rams’ defense looks like an appealing play because of all these injuries. They’re the highest-priced defense on both DraftKings and FanDuel, but it’s worth it to get that type of security. Besides, the Giants don’t have a good offensive line anyway, so Aaron Donald will wreak havoc and Jalen Ramsey will have a chance at interceptions if the Rams can build a lead and make the Giants throw.

Speaking of, the Rams should have a chance to build a lead and lean on the running game in the second half, if not sooner. The Giants have been average against RBs, but they have allowed at least one RB to record 93-plus scrimmage yards in each of their five games this season. That included Ezekiel Elliott’s 112-yard, two-TD performance last week.

Henderson has a TD in three of his four games and has back-to-back games with at least 99 scrimmage yards. He has a high floor in this one and could have a big day, especially since the Rams are coming off a mini-bye.

Jonathan Taylor & Colts D/ST, Colts vs. Texans (DK/FD Stack) 

Taylor was an absolute beast for the Colts on Monday Night Football in Week 5. He caught a 76-yard TD on the first drive and never looked back. All told, Taylor racked up 169 scrimmage yards and two TDs against a solid Ravens defense. He should find success against the Texans, as well.

Houston’s run defense has improved over its 2020 showing, which ranked dead last in yards allowed. However, it has still allowed the seventh-most rushing yards at a mark of 562. It’s limited running back TDs to five total so far, so it’s fantasy points allowed numbers aren’t crazy high.

That said, Damien Harris easily could have scored twice against the Colts last week had he not fumbled at the goal line, and Nick Chubb had nearly 100 yards and a touchdown against the Texans on just 11 carries earlier this season. Taylor will have a chance to post similar production, as he had at least 95 scrimmage yards and a TD in each of his two games against the Texans last year.

Going with the Colts’ defense isn’t a bad play either. They looked great against the Ravens and Lamar Jackson until Xavier Rhodes was knocked out of the game late with an injury. If he can get healthy, the Colts will have a chance to be a top defense for this slate. If not, they still may be able to rattle Davis Mills enough to make this a viable strategy.

Quarterback | Running back | Wide receiver | Tight end | D/ST | Kicker

Week 6 DraftKings, FanDuel Picks: Best stacks for daily fantasy football GPPs/tournaments

QB Taylor Heinicke, WR Terry McLaurin, & TE Ricky Seals-Jones, Washington vs. Chiefs (DK stack)

If you want a bold strategy, this is the one to follow. Washington’s offense has been hit or miss this season with Heinicke taking over for an injured Ryan Fitzpatrick (hip), but this is a great matchup for them.

The Chiefs’ defense has been abysmal so far this year. They are allowing the second-most yards (437.4) and most points (32.6) per game this season. They have yet to limit a team to fewer than 29 points in a single contest.

Maybe Kansas City will slow down Washington a bit, but their defensive struggles aren’t necessarily easy fixes. So, it’s more likely that they’ll continue to flounder even if they can come up with some key stops.

Heinicke seems like the best play. He’s the 12th-highest priced QB on DraftKings and 10th-highest on FanDuel but is playing the bottom-ranked defense against quarterbacks. That will make him a big threat.

As for weapons to stack, you have to go with McLaurin, as he’s averaging 9.8 targets and 80 receiving yards per game. Seals-Jones is a nice sleeper option, as he had eight targets last week as the new starter in place of the injured Logan Thomas (hamstring). He’s only $3K on DK and $5K on FD, so it won’t be hard for him to pay off that price tag, especially in DraftKings’ full-point PPR format.

QB Sam Darnold, RB Christian McCaffrey (or Chuba Hubbard, if McCaffrey is out), & WR D.J. Moore, Panthers vs. Vikings (DK/FD stack)

It sounded like McCaffrey (hamstring) had a chance to return last week before he was ruled doubtful. If he returns this week, you can play him against the Vikings and alongside his top quarterback and receiver.

Darnold and the Panthers’ offense didn’t have a good day against the Eagles in Week 5, blowing a nine-point lead late because they couldn’t move the ball. They’re primed to bounce back against a Vikings defense that has been middle of the pack to start the year.

The Vikings have allowed the 11th-most rushing yards per game this season at 130 a pop. If McCaffrey is healthy, he should get a majority of the opportunities to earn those with Hubbard mixing in occasionally and Darnold helping with his newfound scrambling ability, as well.

The Vikings are better against the pass, but they have had issues against the NFL’s better receivers. Minnesota has allowed seven double-digit fantasy scorers at the wideout position through five weeks. They particularly struggled against DK Metcalf, Ja’Marr Chase, and three of the Cardinals’ receivers, so they will have trouble against Moore, who was targeted nine times and had four catches for 61 yards against the Vikings last year.

Carolina should operate better with McCaffrey in the lineup, as he was for the first two-plus games of the season, but Hubbard, who had over 130 total yards last week with five catches, fits in this stack just fine, too.

RB Joe Mixon & Bengals D/ST, Bengals at Lions (DK Stack)

There are a few ways in which you could attack the Bengals-Lions game, but this seems like the best option.

Mixon (ankle) is a bit banged-up, and it was expected that he wouldn’t play last week. However, he suited up and split carries with Samaje Perine. That seems unlikely to continue into Week 6, as Perine has landed on the COVID list. That leaves Mixon and sixth-round rookie Chris Evans as the only healthy backs on the Cincinnati roster.

The Bengals will probably call up Trayveon Williams or Pooka Williams Jr. to serve as a third RB if Perine is out, but it’s hard to imagine them getting many carries. It’s also hard to imagine Evans handling significant work. As such, Mixon could be the workhorse against a Lions defense that is allowing the fourth-most DK points to RBs this season (31.6). That includes 10 total TDs, good for the most in the NFL.

This is a good week to trust Mixon, and pairing him with the Bengals’ defense isn’t a bad move either. They’re the fifth-highest price defense on the slate, and the Lions average just 19.6 points per game. They also have seven turnovers on the season, and Jared Goff has been sacked 14 times in five games. The Bengals have a high floor, so don’t be afraid to trust them just because they haven’t been a great fantasy defense this year.


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